Can someone explain how this differs from the non-pwm version? Is it just the number of wires? IF so why would one select that over the alternative?

PWM or pulse width modulation is one of several methods to control motor and hence in this case fan speed. The correct motherboard connection as noted below permits the fan speed to be modulated to increase cooling when computing loads are high and slowing the fan at other times. The only benefit being less fan noise.

Can this be mounted in place of a 50x50mm fan?

No, not unless you have room for it and can enlarge the mounting hole pattern and fan hole.

Can you convert this from 4 pin to 2 pin?

It comes with PWM to three pin adapters.... You'd have to hack up your own PWM to DC adapter

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NF-A6x25 PWM

Product ID: 14165352

Details

Air Flow Capacity
29.2 Cubic Per
Brand
Noctua
Compatible Devices
Desktop
Cooling Method
Air
Material
Fibre-glass
Maximum Rotational Speed
3000 RPM

⏳>150,000 h MTTF reliability

🌀3000 RPM max speed

🔇19.3 dB(A) ultra-quiet

Rp848105

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Description

🌀 Silence meets power: cool smarter, not louder.

BUILT TO LAST - Over 150,000 hours of mean time to failure means this fan is your long-term cooling partner.
PRECISION PWM CONTROL - Seamlessly adjust fan speed from 550 to 3000 RPM for perfect thermal balance and energy efficiency.
WHISPER QUIET COOLING - Experience near-silent airflow with advanced acoustic optimization—keep your workspace zen.
VERSATILE COMPATIBILITY - Ideal upgrade for DVRs, NAS, 3D printers, and compact desktops—fit and forget.
COMPLETE INSTALLATION KIT - Includes anti-vibration mounts, extension cables, and Y-splitter for dual fan setups—plug and play perfection.

The Noctua NF-A6x25 PWM is a premium 60x60x25mm 12V fan engineered for ultra-quiet, high-performance cooling. Featuring a 4-pin PWM connector, it offers precise speed control up to 3000 RPM with minimal noise at 19.3 dB(A). Designed with advanced acoustic optimization and Flow Acceleration Channels, it delivers efficient airflow of 29.2 m³/h while maintaining exceptional durability with over 150,000 hours MTTF. Perfect for compact devices like NAS, DVRs, and 3D printers, it comes complete with anti-vibration mounts and cables for easy installation.

Specifications

ASIN	B00VXTANZ4
Air Flow Capacity	29.2 Cubic Meters Per Hour
Best Sellers Rank	#93 in Computer Case Fans
Brand	Noctua
Brand Name	Noctua
Compatible Devices	Desktop
Cooling Method	Air
Customer Reviews	4.8 out of 5 stars 2,696 Reviews
Global Trade Identification Number	00842431012524, 04716123315636
Item Dimensions L x W x H	2.36"L x 2.36"W x 0.98"H
Item Weight	41 Grams
Manufacturer	Noctua
Material Type	Fibre-glass reinforced PBT
Maximum Rotational Speed	3000 RPM
Model	NF-A6x25 PWM
Noise Level	19.3 Decibels
Number of Items	1
Part Number	NF-A6x25 PWM
Power Connector Type	4-Pin
Product Dimensions	2.36"L x 2.36"W x 0.98"H
UPC	842431012524
Unit Count	1.0 Count
Voltage	12 Volts
Warranty Description	6 year manufacturer’s warranty

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